Prozac side effects & safety

Prozac Review – side effects, weight loss, safety

See also :

Prozac Dosage – how much is enough?

Prozac and Safety – who should not take Prozac?

Mixing Prozac with other drugs

Comparisons of Prozac to other treatments for depression

Buying Prozac (fluoxetine) online – a guide

What is Prozac?

Prozac is the leading brand name for the drug fluoxetine.

Other brand names for fluoxetine include:

  • Sarafem,
  • Rapiflux,
  • Selfemra,
  • PROzac
  • Pulvules,
  • Prozep,
  • Olena,
  • Oxactin.

First of all, in this article, the terms ‘Prozac’ and ‘fluoxetine’ are interchangeable.

What is Prozac used for?

prozac reviewThe answer to the question – Why is Prozac prescribed? – is that Prozac, (or fluoxetine), primarily treats depression.

The main type of depression Prozac treats is what psychiatrists call major depressive disorder or clinical depression. (Briefly, a mood disorder where you persistently feel sad and/or lack interest in life).

Additionally, doctors also prescribe Prozac for:

  • bulimia nervosa,
  • obsessive-compulsive disorder (OCD),
  • panic disorder
  • premenstrual dysphoric disorder (PMDD, extremely bad PMS).

Fluoxetine (Prozac) may also be prescribed for bipolar disorder (manic depression), in which case it’s sometimes prescribed along with olanzapine (brand name Zyprexa).

As a result, the Federal Drug Administration (FDA) in the USA has issued official license to Prozac (fluoxine) for treatment of these are the conditions.

However, the FDA has licensed only brand name Sarafem for PMDD, but not Prozac or generic Prozac. (Yet Sarefem is the exact same thing: fluoxetine!)

Other uses of Prozac

Prozac may be prescribed for other conditions too, at a doctor’s discretion. This is referred to as “off-label” uses because they are not uses for which Prozac has been officially approved.

Other uses of Prozac include:

  • ADHD (attention-deficit disorder),
  • alcoholism,
  • anger,
  • anxiety,
  • bipolar disorder,
  • depression,
  • fibromyalgia,
  • headaches,
  • hot flashes,
  • menopause,
  • OCD,
  • pain,
  • PMDD, PMS,
  • PTSD (posttraumatic stress disorder),
  • Raynaud’s syndrome,
  • weight loss
  • Tourette’s syndrome,
  • premature ejaculation
  • phobias.

As mentioned above, fluoxetine is officially approved to treat depression, OCD, PMDD (severe PMS) and bulimia.

Furthermore, research is currently under-way examining the usefulness of Prozac for the treatment of autism spectrum disorders.

However, many of these uses are quite specific to the individual. For example, one Prozac side effect is insomnia, though for some people it does make them drowsy.

Prozac side effects and mood disorders

Another side effect of Prozac is anxiety. As a result social anxiety sufferers are often prescribed Prozac.

Additionally, the medical profession prescribes fluoxetine to help people deal with anger issues. This is because fluoxetine can have a calming effect that helps people deal with difficult emotions.

However, a possible side effects of fluoxetine is aggression, hostility and anger.

prozac side effects

As a short-term treatment for obesity, fluoxetine (Prozac) can be useful. Prozac treats obesity caused be eating more than needed – not for obesity caused by hormonal imbalance.

As for weight loss more generally, in some people it acts as an appetite suppressant and lead to weight loss. In other people it can cause weight gain.

The results are inconclusive for bipolar disorder.

Some people have found success in using Prozac as a short-term treatment for severe depressive episodes.

However, it can cause manic reactions in some people. Therefore in these cases combinations of Prozac and a mood stabilizer drug is employed.

Also, those with bipolar disorder have a greater risk of developing suicidal thoughts.

Prozac as a pain reliever

For pain, it’s found that some antidepressants may disrupt pain signals being transmitted to the brain. It may help with some kinds of chronic pain, including tension headaches and pain associated with fibromyalgia.

However, SSRIs like fluoxetine don’t work so well this way, though they’re good for helping depression associated with chronic pain.

Tricyclic antidepressants are more effective for pain relief. More on that here:

For Raynaud’s syndrome, initial research indicates effectiveness. More studies will to confirm this either way.

How does Prozac (fluoxetine) work?

Prozac is a selective serotonin reuptake inhibitor (SSRI). Serotonin is a neurotransmitter, a chemical which transmits signals between nerves.

How does Prozac affect the brain and the nervous system?

It works like this: an electrical signal travels along a nerve and when it reaches the end, triggers the release of serotonin from the end of the nerve cell into a gap (synapse) between nerves.

Serotonin then stimulates receptors on the next nerve cell. That initiates an electrical signal to travel along that nerve. The first nerve then reabsorbs (re-uptakes) any excess serotonin that’s lying around.

So a selective serotonin reuptake inhibitor is a chemical preventing re-absorbtion of serotonin into the nerves once released.

Therefore more serotonin remains in the nerve synapses (the area between nerves), and consequentially the nerve cells in the brain are activated to respond to serotonin.

Effectively, an SSRI increases serotonin levels, which generally boosts mood, though it’s not clear exactly how it improves depression or even what causes depression.

How effective is Prozac – does it really work?

For mild depression, there’s mixed evidence as to whether Prozac really helps, however studies do show it to be more effective than a placebo for severe depression.

buy fluoxetine onlineKeep in mind that a certain proportion of the effects of any antidepressant can be due to placebo effect.

The placebo effect is a psychological boost you can get from thinking you are taking a medicine and believing it’s working.

Consequentially, this can actually affect physical processes in your brain and body to fulfil those expectations. A placebo effect can affect your health, not just your perceptions.

You should also note that while Prozac may help alleviate symptoms of depression, it doesn’t treat the causes.

So if you’re feeling bad enough to be taking Prozac, then it’s a good idea to be having some kind of counselling or psychotherapy as well in order to try to deal with the underlying roots of your emotional distress or discomfort.

There’s a good UK NHS (National Health Service) article about antidepressants here:

Who invented, developed Prozac / fluoxetine?

Eli Lilly and Company discovered Fluoxetine in 1972 and released Prozac for medical use until 1986.

Who manufactures Prozac and makes generic Prozac available?

Eli Lilly and Company manufactures brand name Prozac. However, their patent has now expired. Generic versions of Prozac are currently widely available.

Safety concerns when using Prozac

Is Prozac safe for you? Who shouldn’t take Prozac.

There are various health conditions which mean taking Prozac may not be safe for you.

Check with a doctor about any other health conditions you have, in case they make Prozac inadvisable, and particularly if you have or have had any of the following:

  • cirrhosis of the liver
  • kidney disease
  • diabetes
  • narrow-angle glaucoma
  • seizures or epilepsy
  • bipolar disorder (manic depression)
  • a history of drug abuse or suicidal thoughts; or …
  • if you are being treated with electro-convulsive therapy (ECT).

is prozac safe?There are various drugs – and even herbs – which interact with fluoxetine and if you’re taking those, you shouldn’t take fluoxetine.

See below for details on what not to take Prozac with.

Obviously, if you know you’re allergic to fluoxetine (Prozac), don’t take it.

If you’re allergic to any foods or medicines or other substances, then tell a doctor in case you turn out to be allergic to fluoxetine also.

Some of the side effects of Prozac can be severe. See directly below for details.

The link between Prozac and increased depression, self-harm and suicide.

One of the major side effects, which the makers of Prozac (Eli Lilly and Company) did not publicize or admit to initially, is that it causes some people to feel more depressed and even think about suicide or self harm.

Young people under about the age of 25 are more prone to this side effect.

This means that as well as going to your doctor or psychiatrist for regular check-ups, you should get close friends or family members to look out for you as well.

It’s often easier for others to spot psychological changes in you than it is for you to notice them yourself, especially if they come on gradually.

So look out for, and have others look out for, changes in your mood or behaviour. Changes to watch out for include becoming (more) anxious, nervous, depressed, panicky, impulsive, irritable, agitated, aggressive or hostile, restless or hyperactive, insomnia, suicidal or self-harm thoughts.

These changes are reported to be more likely when you first start taking fluoxetine (Prozac) or if your dose is altered, though they could happen any time. These side effects are also more likely if you have a history or family history of mental illness, including depression.

Since Prozac is most commonly prescribed for depression, this is not reassuring!

US government Medline website says : No matter your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments.

You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal.

This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or has thought about or attempted suicide.”

What are the other Prozac side effects?

fluoxetine dosageA common side effect is that taking fluoxetine can make you feel dizzy or maybe drowsy and affect your ability to think and react quickly and clearly. So, obviously, don’t drive or operate machinery or do anything else requiring full alertness until you are sure that Prozac is not having that effect on you.

The most common side effects are insomnia, tiredness, headaches, nausea (feeling sick) and diarrhoea.

Other common side effects include: strange dreams, vision changes, tremors or shaking, weakness, pain, fatigue, upset stomach, vomiting, dry mouth, sweating or hot flashes (flushes), stuffy nose, pain in sinuses, sore throat, flu-like symptoms. You can also have changes in your appetite and your weight.

Some common side effects are sexual – lower libido, difficulty having an orgasm, vaginal dryness for women and impotence for men.

You might think those sound quite unpleasant but some people experience more serious side effects, so you must consult a doctor immediately if any of these occur to you:

  • fever,
  • joint pain,
  • swelling of the eyes, hands, feet, ankles, or lower legs,
  • difficulty breathing or swallowing,
  • sweating,
  • confusion,
  • fast or irregular heartbeat,
  • severe muscle stiffness,
  • seeing things or hearing voices that do not exist (hallucinating),
  • seizures.

As with all drugs, there’s a small risk of having an allergic reaction to it so get medical help urgently if you start to develop any signs of allergic reaction, like a skin rash or hives, swelling of your face, lips, tongue, or throat, and/or trouble breathing.

There may be other serious side effects not mentioned here.

A more comprehensive and easy-to-read list of side effects can be found here:

Also, if you take too much fluoxetine, or if you take it in combination with some other drugs, it can increase your serotonin levels too much, resulting in serotonin syndrome with symptoms like

  • agitation,
  • hallucinations,
  • delirium,
  • fast heart rate,
  • dizziness,
  • flushing,
  • muscle tremor or rigidity,
  • nausea, vomiting,
  • diarrhea,
  • worst – you might go into a coma!

Are Prozac side effects permanent?

I can’t find information on this specifically, although Prozac does persist for a long time in your body (several weeks), which means that once you reduce your dose or stop taking it, it could still take a while for side effects to decrease.
Why does Prozac cause weight gain, weight loss, make you tired, make you sleepy?

These are just some of the possible side effects of taking Prozac. However, Prozac is less likely to cause you to gain weight than some other antidepressants, and may cause you to lose weight. It’s also less likely to cause you to feel sleepy or sedated than some other antidepressants and may actually keep you up with insomnia.

Does Prozac change personality?

Well, maybe. Taking Prozac alters the chemistry of your brain. It can make you feel better – more positive and bright, although for some it has very negative side effects including making you more anxious, aggressive and even suicidal. Some people find they feel their emotions are dulled or dampened when taking it. Others find their emotions which have been dulled by their depression become more vibrant again.

Do any of these changes constitute a change in personality? I suppose that depends on how you view personality. Proponents of antidepressants would argue that by alleviating some of the negative effects of depression, they’re revealing your personality, which was otherwise dampened or hidden by your depression.

Is Prozac addictive?

Prozac is not considered to be addictive in the same way that some other medications are, like Valium (diazepam), whereby you can quickly become physically dependent on it, and eventually psychologically dependent on it. However, once you’ve been taking Prozac for a while, your brain does get used to it. This means that if you stop taking it suddenly you can get withdrawal symptoms like headaches, nausea, dizziness, or flu-like symptoms. So it’s important to stop taking Prozac by gradually decreasing your dose.

Is Prozac safe when pregnant or breastfeeding?

Not unless you really have to. Taking Prozac, or any SSRI antidepressant, when you’re pregnant could cause lung or cardiac problems or other complications in your unborn baby. It can also pass into breast milk and could harm your child. If you get pregnant while taking Prozac, or want to, talk to your doctor about it. Same for breastfeeding.

What not to take Prozac with?

You shouldn’t take Prozac with herbs like St John’s Wort, supplements containing tryptophan, and various medications. For details on each of these, see the next two questions below.

Is Prozac safe to take with alcohol, coffee, food, St John’s Wort?

It’s not a great idea to take Prozac with alcohol. The booze can increase the risk and severity of some of Prozac’s side effects. It’s not as risky as it is with some other antidepressants though.

You don’t need to talk Prozac with food but it is okay if you do.

Don’t take Prozac with St John’s Wort. It puts you at risk of serotonin syndrome and may interfere with Prozac’s effectiveness.

Drinking coffee while taking Prozac is okay but be aware that it can produce some similar side effects to Prozac. It might increase your risk of feeling nervous and agitated – especially if you drink a lot of coffee.

Is Prozac safe to take with other medications?

It depends. Fluoxetine is known to interact, sometimes dangerously, with some other medications so – if you’re on any meds at all, or even taking herbs or supplements – this is something you need to check with a doctor or pharmacist.

Prozac and MAO inhibitors

One of the most dangerous Prozac interactions is with MAO (monoamine oxidase) inhibitors, such as

  • isocarboxazid,
  • linezolid,
  • phenelzine,
  • rasagiline,
  • selegiline,
  • tranylcypromine

This is not a complete list.

If you’ve taken an MAO inhibitor medicine in the last two weeks, you shouldn’t take Prozac as it can lead to serotonin syndrome (discussed under Prozac dosage) which can be very serious.

Anti-psychotic drugs like pimozide and thioridazine are also risky combinations with Prozac. You should not take them together. In fact, it must be at least five weeks since you took Prozac before you can take thioridazine.

You should also avoid Prozac if you are having methylene blue injection.

Prozac and NSAIDs

Other medicines which interact with Prozac are non-steroid anti-inflammatory drugs (NSAIDs).

These are medicines usually taken for pain, arthritis, fever, swelling, and include aspirin, and taking these with Prozac can mean you bruise and/or bleed easily.

They include common over-the-counter medications such as:

  • aspirin,
  • ibuprofen (Advil, Motrin, Nurofen),
  • naproxen (Aleve),
  • celecoxib (Celebrex),
  • diclofenac,
  • indomethacin,
  • meloxicam,
  • also many others.

Check with a doctor before you take Prozac if you’re taking any of these (or vice versa).

Also, since Prozac may make you sleepy, any medications which can make you sleepy can make this worse. This includes medicines for anxiety, depression, and seizures, as well as narcotic pain relievers and muscle relaxants, and of course, sleeping pills. Check with a doctor before mixing these meds.

Prozac and other antidepressants

Also, don’t take Prozac with other antidepressants as this can be very dangerous.

This includes but is not limited to

  • other SSRIs like Lexapro,
  • SNRIs like Cymbalta and Effexor,
  • NDRIs like Wellbutrin
  • Tri or Tetracylic antidepressants like Trazodone.

Other medications which interact with Prozac include:

  • Adderall,
  • Lithium,
  • Vyvanse,
  • Xanax.

Again, check with your doctor before mixing these medications.

These are just some of the medicines which can interact with Prozac.

This Prozac review is the result of extensive research and cross comparisons.

A sample list of our references and sources is listed below,

Buy Prozac online

Why buy Prozac online?

Commonly doctors in the UK prescribe Prozac (fluoxetine) and their patients purchase the medication from local pharmacies.

However, for various reasons the option of obtaining a prescription is not open to everyone.

Those excluded from this process, due to money or proximity to a doctor or pharmacy, can buy Prozac online in the UK

As a bonus, those who buy Prozac online get it for much lower costs than charged at UK pharmacies – even after shipping.

Buy Prozac online without a prescription

In most countries including the EU and the UK, you can only legally purchase Prozac with a prescription from a qualified medical professional.

buy prozac onlineHealth and safety regulations stipulate an online consultation prior to buying Prozac online.

An online consultation, if it meets approval, has the same weight as a prescription.

A qualified medical professional, usually a licensed doctor, reviews the consultation and approve the order being sent based on the answers received.

Approval of an online consultation by a doctor has the same legal basis as a prescription issued by GP in a clinic.

The online pharmacy we recommend (see link below) incorporates this consultation process during checkout.

If your order of Prozac is not approved, you are not charged.

The consultation process is provided free of charge whether you are successful or not.

Which generic Prozac is best?

There is no difference between generic Prozac made by generic medication manufacturers and with brand name Prozac made by Eli Lilly pharmaceuticals.

The only difference is in appearance and price.

Generic Prozac capsules may be of a slightly different colour or shape that brand name Prozac. The active ingredients however are identical.

Generic Prozac is a small fraction of the price of brand name Prozac. Patent costs of brand name Prozac can be an additional 500% (or more) to the actual costs of the drug.

Many people prefer to buy Prozac online simply to save money. Top quality cheap Prozac online is now readily available.

Where to get fluoxetine online? Where to buy Prozac in the UK?

generic prozac pill boxBelow we provide links to low price online pharmacies that have a good reputation for good customer service providing quality medications at very competitive prices.

There are a number of online pharmacies where you can buy Prozac online. The pharmacies we list below are our recommendations for best price service and security.

As noted above, these pharmacies offer free consultation service integrated into the checkout process. This enables those who don’t currently have a doctor’s prescription to buy Prozac online.

Click the picture or text link below to view prices and order options for Prozac (fluoxetine).

Prozac (fluoxetine) 20mg, 40mg, 60mg

Prozac was initially approved for the treatment of depression in Belgium in 1986 and in the United States in 1987. Since then, it has been approved and marketed in more than 90 countries.

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If you are not 100% sure fluoxetine (Prozac) is right for you please check out further information from the links below.

Fluoxetine side effects

Safety considerations when taking fluoxetine (Prozac)

Combining fluoxetine with other medications

Fluoxetine doses

Comparing Fluoxetine with other antidepressant medictions

What is the correct fluoxetine (Prozac) dosage?

First of all, take the dosage your doctor prescribed you. If you don’t have a prescription read below for the correct Prozac dosage for your condition.

prozac dosesIt may be different from the usual dosage, but everyone’s different and different health conditions, circumstances.

Other medications, and of course the nature of your symptoms, affect what’s a suitable dose for you.

Take it at the same time every day, with or without food (though if it upsets your stomach at all, try taking it with food).

Secondly, fluoxetine comes as tablets, capsules, a liquid, which are taken daily or extended-release capsules which are generally taken weekly.

If you’re taking delayed-release tablets, then it’s important that you swallow it whole and don’t crush or chew it.

Thirdly, if you want to stop taking it, talk to your doctor about how to do this.

It’s not a good idea to stop taking Prozac suddenly. You might get unpleasant withdrawal symptoms. These include:

  • mood changes,
  • irritability,
  • agitation,
  • dizziness,
  • numbness or tingling in the hands or feet,
  • anxiety,
  • confusion,
  • headache,
  • tiredness,
  • trouble sleeping.

Fourthly, don’t take more than you’re prescribed as taking too much fluoxetine can increase your serotonin levels too much, which can give you serotonin syndrome. For more details see Prozac side effects

Doses can vary a lot, depending on how the individual responds to the drug.

If you are unable to get instructions from a qualified medical professional then it is best to start with a low dose. Only increase dosage in a slow and controlled manner.

Prozac starting dose for depression

For major depressive disorder a starting dose of 20mg each morning. For many sufferers, this would be sufficient to control their depression.

Note that doctors may increase dosage over time for some people but that it should not be more than 80mg per day.

Take doses over 20mg all at once in the morning – or split between morning and noon.

Prozac dosage for OCD

It’s a similar case for obsessive compulsive disorder (OCD) – 20mg each morning to start with, going up to possibly 60mg if needed.

Prozac dosage for anxiety

For panic disorder, 10mg each morning is the usual starting dose, going up to 20mg after a week.

Prozac dosgae for bulimia

For bulimia nervosa, 60mg per day may be needed (again, taken in the morning).

All these dosages are for adults.

More details are here:

But please keep in mind that this is just general information and that these dosages may not be suitable for you, specifically.

Always follow the recommendations of your doctor on how much and how often to take Prozac.

Also note that it’s common for it to take up to four weeks, or longer, for the full effects of fluoxetine to be felt.

Best time of day to take Prozac dosage

It’s recommended say that you should take Prozac in the morning because it can cause insomnia. If you find it makes you sleepy however (this happens too, though less often), then you could ask your doctor if you can take it at bedtime instead.

When does Prozac start to work?

It can take up to a month for you to start noticing the effects of fluoxetine (Prozac) and for your symptoms to improve.

When does Prozac wear off? i.e how long does fluoxetine stay in your system?

Fluoxetine stays in your system longer than other similar antidepressants and can stay in your body for as long as three weeks after you stop taking it.

However, since it affects other brain chemicals too (e.g., oxytocin), these can take longer to return to their previous levels.

What if I miss a dose of Prozac?

If it’s getting close to the time for your next dose of Prozac by the time you realise you’ve missed it, then don’t take it and just take your next dose as usual.

Otherwise, take the dose you missed as soon as you realise. Don’t double up on doses though!

There’s also a weekly version of Prozac. If you miss taking one of these, then take it as soon as you remember, and then take your next dose seven days later.

Unless it’s almost time for your next dose, in which case, just leave it and wait till it’s time for your next one.

Again, don’t take extra to make up for missing a dose.

What to do when Prozac no longer works?

Some people just don’t respond much to Prozac. Other antidepressants may work better for you so discuss this with your doctor.

You could also try herbal treatments like St John’s Wort. To read more about that see Prozac comparisons below.

Regular exercise is also proven to help alleviate depression, especially if it’s not too severe.

There are various therapies that could be really beneficial, including cognitive behavioural therapy.

Click here for more suggestions:

See below for more information on Prozac:

How Prozac works to lift depression

Prozac comparison with other treatments for depression

This post looks at the differences between Prozac (fluoxetine) and other similar treatments for depression and anxiety.

Is Prozac the same or similar to:

  • Adderall, Celexa (citalopram),
  • Cymbalta (duloxetine),
  • Effexor (venlafaxine),
  • fluoxetine,
  • Lexapro (escitalopram),
  • Lovan,
  • Paxil (paroxetine)
  • Sarafem,
  • Valium (diazepam),
  • Wellbutrin (buproprion),
  • Xanax (alprazolam),
  • Zoloft (sertraline) ?

Prozac, fluoxetine, Lovan and Sarafem are the same.

Prozac, Lovan and Sarafem are brand names for fluoxetine.

Sarafem is the brand name which targets the treatment of PMDD (premenstrual dysphoric disorder).

Some of the drugs listed here are similar to fluoxetine (Prozac) in that they are also selective serotonin reuptake inhibitors (SSRIs) so work the same way in the brain.

These include:

  • citalopram (Celexa, Cipramil),
  • escitalopram (Lexapro, Cipralex),
  • paroxetine (Paxil, Paxil CR, Pexeva, Seroxat) and
  • sertraline (Zoloft, Lustral).

Others are newer antidepressants. Some are serotonin and noradrenaline (norepinephrine) reuptake inhibitors (SNRIs).

comparisons with fluoxetineThese increase not just serotonin levels but also noradrenaline levels in the brain and include duloxetine (Cymbalta, Yentreve) and venlafaxine (Effexor).

Thus they tend to increase alertness and energy as well as positive mood. Wellbutrin (buproprion) is a noradrenaline and dopamine reuptake inhibitor (NDRI) so increases noradrenaline and dopamine levels.

Fluoxetine is not like Adderall, which is an amphetamine-based medication for ADHD (attention deficit and hyperactivity disorder), though Adderall is like speed.

Fluoxetine is sometimes prescribed to treat ADHD though, though it is not licensed for this use.

Valium (diazepam) and Xanax (alprazolam) are benzodiazepine drugs which are mainly used for treating various kinds of anxiety and panic disorder.

Which is better, Prozac (fluoxetine) versus

  • Celexa, Cipramil, (citalopram),
  • Cipralex (escitalopram),
  • Cymbalta (duloxetine),
  • Effexor (venlafaxine),
  • Lexapro (escitalopram),
  • Paxil (paroxetine),
  • Pristiq (desvenlaxafine),
  • St John’s Wort,
  • Wellbutrin (buproprion),
  • Xanax (alprazolam),
  • Zoloft (sertraline)?

Prozac compared to other SSRI medications

SSRIs including Prozac are usually the first types of antidepressants to be prescribed for depression as they generally have fewer side effects and an overdose can be less serious.

However, they’re not necessarily more effective.

The American Psychiatric Association states that “effectiveness of antidepressants is generally comparable between and within classes of medications, including SSRIs, SNRIs, TCAs, MAO inhibitors, and other antidepressants […] For most patients, an SSRI, SNRI, mirtazapine, or bupropion is considered optimal (e.g., bupropion, mirtazapine, trazodone).” See: for more information.

prozac comparisonDifferent people react differently to different medications, so there’s no general answer to which antidepressant is better than another. It depends.

Since they have different contraindications, some might be more or less suitable for you, depending on your specific health conditions.

Prozac side effects are another consideration. While Prozac generally produces less side effects than other types of antidepressant, it may have side effects for you that you cannot tolerate.

For example, sexual dysfunction is some of the most common side effects of fluoxetine including decreased sex drive, difficulty orgasming, vaginal dryness or impotence.

Wellbutrin (buproprion) is a different antidepressant and does not have sexual dysfunctional side effects. Doctors occasionally prescribe Wellbutrin along with Prozac to counteract these undeirable side effects.

There’s a good article on SSRI antidepressants and their pros and cons here:

St John’s Wort is a yellow flowering plant that has similar effects in the brain to SSRI medicines like Prozac. It may also have other effects.

There’s mixed evidence as to how effective St John’s Wort is.

Whatever you do, don’t take it at the same time as taking an antidepressant medication as the two may interact with negative effects on you.

Prozac as an anxiety relief medication

For anxiety, other SSRI’s are used for treating it, including Celexa and Cipramil (citalopram) and Lexapro and Cipralex (escitalporam) – though fluoxetine (Prozac) isn’t.

SNRIs, like Effexor (venlafaxine) and Cymbalta (duloxetine) meet approval for some types of anxiety relief.

Xanax (alprazolam) is a completely different drug (a benzodiazepine). Xanax is an effective treatment for anxiety – though has a greater risk of addiction.

Consequently some doctors prescribe SSRIs in preference to Xanax for anxiety relief.

Prozac compared to other antidepressants pain relief

For pain relief, other antidepressants are better than fluoxetine, including SNRIs such as Cymbalta (duloxetine) and tricyclic antidepressants.

If you are treating bulimia, fluoxetine or other SSRIs is a better choice due to less adverse effects.